1:10:404K views
Latest long-form episode
High ApoB, CAC Zero: What Your Heart Tests Are Really Saying
Jul 10, 2026Open episode
Podcast
The Longevity Show
Conversations on longevity medicine, preventive care, metabolic health, heart risk, hormones, exercise, nutrition, and clinical AI. We start with how things work, not with the headlines.
What the show covers
A practical longevity medicine podcast for people who want the mechanism, not just the headline.
Cardiovascular prevention: ApoB, Lp(a), CAC scoring, CCTA, and lipid treatment
Metabolic health: glucose, insulin resistance, GLP-1s, nutrition, and body composition
Hormones and women's health: dynamic testing, perimenopause, sleep, and training context
Exercise for longevity: Zone 2, strength, VO2 max, recovery, sauna, and daily movement
Oral and environmental health: periodontal risk, toxins, air quality, and practical exposure reduction
Clinical AI and care models: better inputs, patient agency, and preventive systems that actually work
59 episodes
1:10:40
4K views
Jul 10, 2026
High ApoB, CAC Zero: What Your Heart Tests Are Really Saying
High ApoB but clean metabolic labs. CAC zero but inherited Lp(a). A normal stress test but plaque on CCTA. This is where heart-disease prevention gets noisy. In this advanced episode, I walk through how I read conflicting heart-risk signals without letting one lab, scan, or internet camp hijack the whole conversation. The map is simple: particle traffic, the artery wall, blood pressure and metabolic terrain, visible plaque, and the clot we are trying to prevent. We cover ApoB, LDL-C, LDL-P, particle size, Lp(a), APOE4, CAC, CCTA, CIMT, stress testing, inflammation, plaque reversal, statin concerns, supplements, and what actually changes the next decision. Use this as education and a framework for better clinician conversations, not a personal treatment plan. *Chapters* 00:00 Why Heart Tests Seem To Disagree 01:43 The Map: Particles, Wall, Terrain, Plaque, Event 06:22 Where Plaque Actually Begins 10:07 Why Evolution Left Us Vulnerable 13:22 ApoB, LDL-C, LDL-P, Particle Size, Remnants, Lp(a) 25:54 High ApoB With Clean Metabolic Markers 30:51 Blood Pressure, Inflammation, And “Terrain” 35:37 APOE4, Family History, And Inherited Clues 40:38 CAC, CCTA, CIMT, Stress Tests, And AI Plaque Analysis 48:26 How To Read Conflicting Signals In Real Life 50:26 Plaque Reversal, Stabilization, And What Counts As Proof 54:18 Statins, Side Effects, Red Yeast Rice, And Supplement Claims 01:09:45 The Takeaway: Do Not Let One Marker Become The Whole Story Get Dr. Hillary Lin’s free longevity tips and newsletter: https://hillarylinmd.com/go/yt Learn more about the podcast: https://hillarylinmd.com/podcast LinkedIn: https://www.linkedin.com/in/hillarylinmd/ Learn more about Dr. Hillary Lin: https://www.hillarylinmd.com/ Explore CareCore: https://carecore.io --- Watch next: https://youtu.be/AtOTY0x3U3I
Show notes
Jul 8, 2026
Why Normal Labs Miss Your Fitness Decline
Standard lab panels can look normal while cardiorespiratory fitness quietly declines. VO2 max is one of the strongest predictors of long-term mortality, yet it rarely shows up on a routine blood draw. In this conversation, Brooks Leitner of VO Health explains why the gap exists and what it would take to close it.
42:11
658 views
Jun 10, 2026
Cortisol Is a Curve: Why One Hormone Test Can Mislead You
This episode features Marina Rivas, cofounder/CEO of Eli Health. Educational only: wellness hormone trend data is not diagnosis or treatment. A single morning cortisol or hormone lab can miss timing, wake time, sleep, stress, training, cycle context, and recovery patterns. But symptoms, abnormal results, HRT/TRT decisions, adrenal concerns, and medication/supplement changes belong with a qualified clinician. We discuss what cortisol curves and hormone trends may reveal, what one lab can miss, and why more testing is not automatically better. We cover: - why hormones are patterns, not single data points - cortisol curves vs cortisol panic - saliva testing and what it can/can’t show - progesterone and testosterone tracking - wellness data vs clinical diagnostics - why validated at-home testing is hard - how AI in healthcare depends on better biological inputs Learn more about the podcast: https://hillarylinmd.com/podcast Newsletter: https://hillarylinmd.com/go/yt LinkedIn: https://www.linkedin.com/in/hillarylinmd/ Eli Health: https://eli.health/ CareCore: https://carecore.io Educational only. This video does not constitute medical advice, diagnosis, or treatment, and no doctor-patient relationship is formed. Chapters: 00:00 Hormones are patterns, not snapshots 00:54 Why annual hormone testing misses context 02:43 How at-home saliva testing works 06:17 Cortisol curves vs cortisol panic 12:14 Why timing and baseline matter 15:05 Stress, training, and overtraining signals 18:43 Progesterone and testosterone tracking 20:40 Trends vs noise in hormone data 23:44 Designing testing people can actually use 24:40 Cortisol, performance, and recovery 28:31 What changes testosterone levels? 31:36 Wellness data vs clinical diagnostics 35:18 AI needs better biological inputs 37:39 Why health hardware takes years to build 39:04 What longevity-minded people should take away — Watch next: https://www.youtube.com/watch?v=XJ-qv9VBKqo
HormonesCortisolWomen's Health
54:02
4K views
May 25, 2026
Your Workout Might Be Making You Older
What if your workout is not the problem, but the way you recover from it is? In this episode of The Longevity Show, Dr. Hillary Lin talks with performance coach Kyle Gonzalez about the difference between training that builds healthspan and training that can backfire because recovery, intensity, and context are mismatched. We cover how to build a smarter longevity training week: movement throughout the day, aerobic base, strength, balance, power, glucose control, sleep, recovery, Zone 2, HIIT, sauna, cold exposure, rucking, barefoot training, HRV, protein, creatine, and the recovery hierarchy. The useful frame is not “exercise less.” It is training with enough stress to adapt, enough recovery to benefit, and enough context to avoid turning fitness into another source of burnout. Important: this episode is educational and is not medical advice or a personalized training plan. If you have cardiovascular disease, diabetes, injuries, chronic illness, pregnancy/postpartum considerations, eating-disorder history, or you are considering supplements, peptides, heat/cold exposure, or a major training change, work with a qualified clinician and coach. Chapters 00:00 Is Your Workout Aging You? 01:01 Exercise vs. Movement: What Medicine and Fitness Get Wrong 02:25 The Sedentary Trap: Why 30 Minutes Isn’t Enough 07:10 All Movement Counts: Even When Your Wearable Misses It 09:25 Training for Life, Healthspan, and Peak Span 11:59 Stress + Rest = Growth: Why Recovery Is Training 15:02 Sleep, Breathwork, Mobility, and the Recovery Stack 19:46 HIIT vs. Zone 2: What to Do When You’re Short on Time 21:42 The 1% Rule: 150 Minutes Is Only 1% of Your Week 25:08 Environment Beats Willpower: Designing a Movement-Friendly Life 29:04 Movement Is the Umbrella; Exercise Is One Piece 30:51 Blue Zones, Ground Sitting, and the Shapes Your Body Adapts To 33:27 Why Outdoor Movement Trains Your Brain Too 35:36 Mitochondrial Health: Zone 2, VO2 Max, and Hormesis 41:11 Protein, Hydration, Creatine, and the Recovery Hierarchy 44:48 Which Health Metrics Actually Matter? 46:38 Rapid Fire: Sauna, Cold Plunge, Rucking, Barefoot Training, HRV 52:08 Kyle’s Book: Move, Thrive, and Come Alive Get Dr. Hillary Lin’s free longevity tips and newsletter: https://hillarylinmd.com/go/yt LinkedIn: https://www.linkedin.com/in/hillarylinmd/ Learn more about Dr. Hillary Lin: https://www.hillarylinmd.com/ Explore CareCore: https://carecore.io Kyle Gonzalez: https://thevitalitysystem.co/ Kyle’s podcast: https://podcasts.apple.com/us/podcast/the-vitality-system/id1727272395 Kyle’s book, Move, Thrive, and Come Alive: https://www.amazon.com/Move-Thrive-Come-Alive-Science-Backed/dp/1572843667 — Watch next: https://www.youtube.com/watch?v=2VKsdrOryVw
ExerciseRecoveryVO2 Max
1:02:56
44K views
May 7, 2026
I Treat Cholesterol Differently Now: Statins, PCSK9s, Ezetimibe & Gene Editing
There is a drug in clinical trials right now that could permanently fix your cholesterol with a single infusion. Once. That's where we're headed. But there's also a $4 generic that's saved millions of lives — and a twice-a-year injection most patients have never heard of. I'm a Stanford-trained physician. My ApoB was 128. My grandfather died of a stroke. My grandmother died of cardiac arrest. My father is recovering from a heart transplant. In this video, I break down every lipid-lowering option available — without hedging, without liability speak — so you can have an intelligent conversation with your doctor. WHAT YOU'LL LEARN: - Why there's no floor for ApoB — the cholesterol-years concept that changes when you start treatment - The genetics checkpoint: Lp(a), FH, and ancestry factors that change your drug selection entirely - Statins: muscle pain reality, the nocebo effect (SAMSON trial), SLCO1B1 gene, CAC paradox, diabetes signal - Ezetimibe: the most underused $15/month drug in lipid medicine (IMPROVE-IT data) - Bempedoic acid: why it structurally cannot cause muscle toxicity, and what CLEAR Outcomes proved - PCSK9 inhibitors: FOURIER + ODYSSEY data, insurance battle, patient assistance programs - Inclisiran: twice a year, doctor administers — why adherence changes everything - Lp(a) pipeline: pelacarsen, olpasiran, muvalaplin — what's coming for the 1 in 4 - Obicetrapib: oral pill hitting BOTH LDL and Lp(a) - Gene therapy: CRISPR + base editing — one injection, once in your life - Lifestyle: honest ceiling assessment, no guilt - A tiered protocol framework using ApoB as the treatment target - What to actually say to your doctor — 6 specific questions Chapters: 0:00 The cholesterol treatment playbook 05:11 Genetics Checkpoint 07:51 Statins 16:16 Ezetimibe 18:45 Bempedoic Acid 25:46 PCSK9 Inhibitors 37:20 Inclisiran 39:46 Lp(a) 44:00 Emerging Therapies + Gene Therapy 52:32 Lifestyle 56:11 Protocol Framework 59:04 What to Say to Your Doctor LINKS: Part 1 — The Disease (Atherosclerosis): https://youtu.be/fX33g1zFZSo Part 2 — The Testing (Why Your Lipid Panel Isn't Enough): https://youtu.be/AtOTY0x3U3I Part 4 — The Genetics: (COMING SOON) Newsletter — The Longevity Letter: https://hillarylinmd.com/go/yt LinkedIn: https://www.linkedin.com/in/hillarylinmd/ Follow me: Instagram: https://instagram.com/hillarylinmd Twitter/X: https://twitter.com/hillarylinmd CareCore: https://carecore.io DISCLAIMER: This video is for educational purposes only and does not constitute medical advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication or treatment. Drug dosing, insurance coverage, and clinical guidelines referenced in this video may have changed since filming. I am a physician but I am not your physician. KEY STUDIES REFERENCED: - CTT Meta-analysis: 170,000+ patients, 22% event reduction per 1 mmol/L LDL (Lancet 2012) - IMPROVE-IT: ezetimibe outcomes, 18,000 patients (NEJM 2015) - FOURIER: evolocumab, 27,500 patients, LDL median 30 mg/dL (NEJM 2017) - FOURIER-OLE: 8.6-year follow-up, no safety signal at LDL ‹ 20 (Circulation 2023) - ODYSSEY OUTCOMES: alirocumab, 18,924 post-MI patients (NEJM 2018) - SAMSON trial: 90% of statin symptoms also occurred on placebo (NEJM 2020) - CLEAR Outcomes: bempedoic acid, 14,000 statin-intolerant patients (NEJM 2023) - ORION-10/11: inclisiran, sustained 50-52% LDL reduction (NEJM 2020) - VICTORION-2P: inclisiran outcomes trial, ongoing - OCEAN(a) Phase 2: olpasiran, › 95% Lp(a) reduction (NEJM 2023) - Lp(a)HORIZON: pelacarsen outcomes trial, 8,000+ patients, ongoing - VERVE-101 heart-1: base editing PCSK9 (Lancet ~2024) - NTLA-2001 Phase 1: CRISPR PCSK9 editing (2024) - Ference et al.: Mendelian randomization, lifetime LDL (EHJ 2017) #cholesterol #ApoB #statins #PCSK9 #inclisiran #genetherapy #lipids #longevity #heartdisease #preventivemedicine #atherosclerosis #cardiovascular #LDL #lipidplaybook — Watch next: https://www.youtube.com/watch?v=fX33g1zFZSo
50:16
18K views
Apr 15, 2026
The Modern Lipid Playbook Part 2: THE TESTING — Why Your Lipid Panel Isn't Enough
The Modern Lipid Playbook Part 2: THE TESTING — Why Your Lipid Panel Isn't Enough 🚨 2026 ACC/AHA Dyslipidemia Guidelines just dropped — the first update in 8 years. Eleven specialty societies declared ApoB and Lp(a) standard of care. The standard lipid panel is officially not enough. My patient "David" did everything right for 25 years. His LDL was in the 40s — below even the NEW aggressive target. His stress test was normal. But his Lp(a), a genetic risk marker no one had ever checked, was nearly 3x the danger threshold. His CAC score: 1,522. His widowmaker artery: 75-99% blocked. Weeks later, he needed an emergent stent. His wife? Same household. CAC: zero. His brother? CAC: 2,700. In this episode, I break down every blood test and imaging test for heart disease — what each one measures, what it misses, and why CCTA (coronary CT angiography) with AI should be first-line imaging for anyone at risk. 📋 WHAT YOU'LL LEARN: • Why LDL-C is a calculated estimate from a 1972 equation — and why it misses 1 in 5 patients • ApoB — the $15 test now in the formal clinical risk algorithm • Lp(a) — the genetic marker every adult should know (universal screening recommended) • Why "passing a stress test" may be the most dangerous false reassurance in cardiology • CAC scores — useful but completely blind to the plaque most likely to kill you • CCTA + AI — how it cut heart attacks 41% in SCOT-HEART (sustained at 10 years) • CPT 75577 — AI plaque analysis is now covered by Medicare (effective Jan 2026) • A tiered testing playbook with real costs and insurance tips • How to talk to your doctor when they won't order the right tests Chapters: 00:00 25 Years on a Statin — and Still Missed 00:27 The 2026 Guidelines Changed the Standard 01:56 The Standard Lipid Panel’s 1972 Flaw 06:38 ApoB and Lp(a): The Two Tests That Change the Story 13:24 The Truth About Advanced Panels, HDL, & Triglycerides 16:30 The Metabolic Fire: Fasting Insulin & hs-CRP 20:18 Why “Passing a Stress Test” Creates Dangerous False Reassurance 27:19 The CAC Score: Useful, but Blind to Soft Plaque 33:30 CCTA & AI: The New Gold Standard for Plaque Detection 42:15 Insurance Coverage, Microvascular Disease, and Who Gets Missed 46:29 The Tiered Testing Hierarchy & Your Personal Playbook 🔗 LINKS: Part 1 — Why Atherosclerosis Matters: https://youtu.be/fX33g1zFZSo ClearCardio Interview with Dr. John Osborne: https://youtu.be/ihJmKmRC65w Newsletter — The Longevity Letter: https://hillarylinmd.com/go/yt LinkedIn: https://www.linkedin.com/in/hillarylinmd/ 📱 Follow me: Instagram: https://instagram.com/hillarylinmd Twitter/X: https://twitter.com/hillarylinmd CareCore: https://carecore.io KEY STUDIES REFERENCED: • 2026 ACC/AHA Dyslipidemia Guidelines (11 specialty societies; replaces 2018 guidelines) • Sachdeva et al., AHJ 2009 (LDL less than 130 in 72.1%, less than 100 in 49.9% at MI; N=136,905) • Friedewald et al., Clin Chem 1972 • Martin et al., JAMA 2013 (Martin-Hopkins; N=1.35M) [verify JAMA vs. JAMA Intern Med] • Walldius et al., Lancet 2001 (AMORIS; ApoB/ApoA-I ratio; N=175,553) • UK Biobank multimodal risk prediction, JACC (PRS + ApoB + hsCRP; N≈500,000) • Mora et al., Circulation 2009 (LDL-C/ApoB discordance) • Wilkins et al., JACC 2016 (CARDIA 25-year follow-up) • Ference et al., JACC 2018 (Mendelian randomization, lifetime LDL) • Falk et al., Circulation 1995 (~60-68% of MIs from less than 50% stenosis) • Glagov et al., NEJM 1987 (compensatory remodeling) • SCOT-HEART, NEJM 2018 (41% MI/death reduction; N=4,146) • SCOT-HEART 10-year, Lancet 2025 (sustained benefit) • PROMISE, NEJM 2015 (CCTA vs. functional testing; N=10,003) • MESA (Detrano et al., NEJM 2008; multi-ethnic CAC; N=6,814) • Ridker et al., NEJM 2008 (JUPITER; N=17,802) • Ridker et al., NEJM 2017 (CANTOS; N=10,061) • CTT Meta-analysis (170,000+ participants; 22% reduction per mmol/L LDL lowering) • WISE Study (women, non-obstructive CAD mortality) • PESA Study, Circulation 2015 (N=4,184) • MASALA Study (South Asian cardiovascular risk) • Mandsager et al., JAMA Netw Open 2018 (VO2 max; N=122,007) • PROMINENT Trial, NEJM 2022 (N=10,497) • CRISP-CT, Lancet 2018 (pericoronary fat; N=3,912) • BROADWAY Trial (obicetrapib; conference data — verify full pub status) • KETO-CTA Trial, JACC Advances 2025 (Norwitz/Feldman; LMHR + CCTA) • Varbo et al., JACC 2013 (Copenhagen remnant cholesterol MR) #cholesterol #heartdisease #ApoB #CCTA #longevity #preventivemedicine #atherosclerosis #lipids #CCTAscan #2026guidelines — Watch next: https://www.youtube.com/watch?v=fX33g1zFZSo This video is educational only and not medical advice. Lipid and cardiovascular decisions depend on your full history — please work with your own clinician.
1:32:44
1K views
Apr 3, 2026
The Toxic Wellness Myths Aging You Faster (Cycle Syncing, Plastics & Noise) with Non-Toxic City Girl
A doctor-led conversation with Jiyeon of NonToxicCityGirl on separating useful low-tox habits from fear-based wellness marketing: plastics, indoor air, noise, cycle syncing, fertility uncertainty, and the basics that matter most. The useful frame is not “everything is poisoning you.” It is: name the specific exposure, understand how strong the evidence is, reduce high-contact/high-heat/high-dose risks where practical, and keep the fundamentals first — movement, sleep, metabolic health, ventilation, and clinician-guided decisions. Note: this conversation includes emerging science, personal stories, and discussions of medications, fertility, cancer metabolism, HRT, rapamycin, LDN, peptides, and supplements. It is educational only and does not constitute medical advice. Do not start, stop, or change prescriptions, fertility treatment, cancer diets, hormones, supplements, or experimental/off-label therapies based on this video; talk with a qualified clinician. Chapters: 00:00 Intro: low-tox living without panic 00:49 Why longevity trends can mislead 03:03 Rational biohacking vs. reckless experimentation 06:49 AI for personal health research — not medical advice 20:03 Why healthcare evidence takes years to reach patients 25:41 How to vet health advice with AI and critical thinking 36:12 Low-tox living: plastics, PFAS, indoor air and noise 47:20 Movement as the highest-ROI longevity tool 51:24 Fertility uncertainty, endocrine disruptors and reproductive optionality 01:08:28 City living, noise, stress and longevity 01:13:14 Body recomposition, sugar, inflammation and metabolic health 01:21:53 Mitochondria, metabolic health and wellness myths About the Show:The Longevity Show with Dr. Hillary Lin takes complex medical research and distills it into practical, easy-to-understand advice for living a longer, healthier life. Covering everything from preventative medicine and metabolic health to the latest breakthroughs in nutrition, exercise, and mental wellness, Dr. Lin gives you the tools you need to thrive. ABOUT DR. HILLARY LIN: Dr. Hillary Lin is a Stanford-trained physician and the Co-Founder/CEO of CareCore. She explores the cutting edge of longevity medicine, metabolic health, and mental resilience, translating complex science into actionable protocols for a longer, healthier life. GET PERSONALIZED INSIGHTS: Newsletter: https://hillarylinmd.com/go/yt LinkedIn: https://www.linkedin.com/in/hillarylinmd/ Instagram: https://instagram.com/hillarylinmd Twitter/X: https://twitter.com/hillarylinmd CareCore: https://carecore.io DISCLAIMER: Content is for educational purposes only and does not constitute medical advice. Consult your physician for medical decisions. — Watch next: https://www.youtube.com/watch?v=N3p6okVW9JU
57:32
2K views
Mar 10, 2026
The $500M Performance Myth: What Tom Brady’s Former Chef Actually Fed Him
Tom Brady’s diet became internet mythology. In this episode, Chef Allen Campbell, who cooked for Brady during part of the TB12 era, joins Dr. Hillary Lin to separate the celebrity-diet story from what ordinary people can actually use: whole foods, adequate protein, fiber, personalization, restaurant choices, and knowing when restriction goes too far. The point is not to copy Tom Brady, avoid every nightshade, or turn food into another rigid protocol. We talk about what shaped Chef Allen’s approach, why context matters, and how to think about food quality, cooking oils, supplements, keto/carnivore trends, organic shopping, and performance nutrition without pretending one diet fits everyone. Important caveat: this conversation is educational only. AC Kitchen examples and personal experiences are anecdotes, not disease-treatment claims. Discussions of cooking oils, gluten/dairy, pesticides, supplements, IVs, keto, carnivore, or organic foods should not be treated as medical advice or proof that a specific food exposure caused a specific disease. If you have a medical condition, lipid concerns, GI disease, cancer concerns, are pregnant, or are considering major diet changes, supplements, or IVs, work with a qualified clinician. What You'll Learn: - Why celebrity diets are often misread - What to borrow from elite performance nutrition without copying every restriction - Why personalization, calories, protein, fiber, and adherence matter - How to think about restaurant choices and cooking oils with more nuance - Where supplements and specialty diets may fit, and where they can backfire - A practical way to prioritize organic food without panic Chapters: 02:59 Personalized Nutrition Philosophy 07:05 Customizing Nutrition at Scale 10:54 Inflammatory Triggers & The TB12 Myth 22:25 Life as a Chef: Passion vs. Business 27:37 Sourcing Organic & Clinical Diet Protocols 35:29 Protein Sourcing & Caloric Realities 42:51 Nutritional Investing & Self-Worth 46:10 Nutrition Trends and Their Impact About Chef Allen Campbell: Allen Campbell is a chef, entrepreneur, and former private chef connected to the TB12 era. His work focuses on high-performance food, personalization, and making healthier meals more practical. Website: https://allencampbell.com/ Instagram: https://www.instagram.com/chefallencampbell X: https://x.com/chefalcampbell #PerformanceNutrition #TomBrady #Nutrition #Longevity #Healthspan ✨ Get 5 Easy Longevity Tips & Dr. Hillary Lin's Weekly Newsletter for Free: https://hillarylinmd.com/go/yt About the Show: The Longevity Show with Dr. Hillary Lin takes complex medical research and turns it into practical, clinically grounded guidance for living a longer, healthier life. Topics include preventive medicine, metabolic health, cardiovascular risk, brain health, nutrition, exercise, testing, and the tradeoffs behind popular longevity trends. About Dr. Hillary Lin and CareCore: Dr. Hillary Lin is a Stanford-trained physician and co-founder/CEO of CareCore, a platform helping clinicians and founders build personalized, evidence-informed longevity practices. Follow for clear, science-rich conversations about healthspan, medicine, and the future of care delivery. Connect with Dr. Hillary Lin: 📩 Free Weekly Newsletter: https://hillarylinmd.com/go/yt 🔔 YouTube: https://www.youtube.com/@hillarylinmd 📸 Instagram: https://www.instagram.com/hillarylinmd 💼 LinkedIn: https://www.linkedin.com/in/hillarylinmd/ 𝕏 Twitter/X: https://twitter.com/hillarylinmd ▶ TikTok: https://www.tiktok.com/@hillarylinmd 📘 Facebook: https://www.facebook.com/hillarylinmd 🏥 CareCore: https://carecore.io Disclaimer: This podcast is for informational purposes only and does not constitute medical advice, diagnosis, or treatment. It is not a personalized nutrition plan, disease-treatment recommendation, supplement/IV protocol, cancer-prevention claim, or endorsement of copying any celebrity diet. Dr. Lin discusses her own experience in parts of the conversation; personal experience should be treated as anecdote, not medical or purchasing advice. No doctor-patient relationship is formed. Use of this information is at your own risk. — Watch next: https://www.youtube.com/watch?v=N3p6okVW9JU
NutritionPerformanceDiet
48:37
3K views
Feb 21, 2026
The Oral Microbiome: What Your Dentist Can Tell You About Whole-Body Health
Oral health is one of the most overlooked parts of whole-body prevention. In this episode, I sit down with Dr. Jonathan Levine to talk about the oral microbiome, periodontal inflammation, airway and sleep, fluoride, oral cancer screening, and emerging diagnostics in dentistry. A key theme: the mouth can offer important clues about inflammation, infection risk, sleep/airway issues, and metabolic health — but oral-systemic links should be understood as associations, risk markers, and plausible mechanisms, not simple one-cause/one-disease claims. This conversation is educational and is not a substitute for dental or medical care. We also discuss where newer tools like 3D imaging, AI-assisted dental exams, and salivary testing may fit — and where the basics still matter: routine dental care, brushing, flossing/interdental cleaning, fluoride when appropriate, sleep/airway evaluation when clinically indicated, and collaboration between dentistry and medicine. Mention of a clinic, product, or diagnostic tool in this conversation is not a universal recommendation. Please work with your own dentist/physician for decisions about imaging, airway evaluation, salivary testing, dental procedures, or treatment. Topics Covered: • Why dentistry and medicine became separated — and why that gap matters for prevention. • The oral microbiome and periodontal inflammation as whole-body health signals. • What we know, and don’t know, about links between gum disease, cardiovascular risk, diabetes, dementia, autoimmune disease, and cancer. • How dental exams, 3D imaging, and AI-assisted tools may help identify structural or airway issues. • Airway, mouth breathing, nitric oxide, and sleep — including why interventions should be individualized. • Salivary diagnostics and oral microbiome testing: promising, but still emerging. • Practical oral-health basics: brushing, flossing/interdental cleaning, tongue cleaning, fluoride decisions, mouthwash choices, and regular dental care. • Oral cancer screening and why dental access matters. About Dr. Jonathan Levine: Dr. Jonathan Levine is a prosthodontist, clinical innovator, and oral-systemic health advocate based in New York City. He is the inventor of GLO Science technology, co-founder of Smile House, and co-founder of the GLO Good Foundation. His work focuses on preventive dentistry, oral-systemic health, advanced diagnostics, and expanding access to dental care. Website: https://www.drjonathanlevine.com/ Instagram: https://www.instagram.com/drjonlevine/ JBL New York City: @jblnewyorkcity Smile House Tribeca: @smilehousetribeca GLO Science: @gloscience GLO Science Pro: @glosciencepro GLO Good Foundation: @glogoodfoundation Chapters 00:00 The Overlooked Role of Oral Health in Longevity 03:10 Rebuilding the Dental Care Model 06:19 The Center for Dental Longevity & Smile House 11:14 The Oral-Systemic Connection 14:33 Integrating Dentistry with Overall Health 20:07 The Tech-Enabled Dental Exam 22:28 Airway Health, Nitric Oxide, & Sleep 29:51 The Future of Salivary Diagnostics 31:12 Mission Work in Dental Deserts 34:06 High-Performance Oral Protocols 36:48 The Role of Fluoride in Dental Health 39:17 Epigenetics vs. Genetics in Decay 46:04 Top Takeaways for Oral Longevity About the Show: The Longevity Show with Dr. Hillary Lin takes complex medical research and distills it into practical, easy-to-understand advice for living a longer, healthier life. Covering everything from preventative medicine and metabolic health to the latest breakthroughs in nutrition, exercise, and mental wellness, Dr. Lin gives you the tools you need to thrive. ABOUT DR. HILLARY LIN: Dr. Hillary Lin is a Stanford-trained physician and the Co-Founder/CEO of CareCore. She explores the cutting edge of longevity medicine, metabolic health, and mental resilience, translating complex science into actionable protocols for a longer, healthier life. GET PERSONALIZED INSIGHTS: Newsletter: https://hillarylinmd.com/go/yt LinkedIn: https://www.linkedin.com/in/hillarylinmd/ Instagram: https://instagram.com/hillarylinmd Twitter/X: https://twitter.com/hillarylinmd CareCore: https://carecore.io DISCLAIMER: Content is for educational purposes only and does not constitute medical advice. Consult your physician, dentist, or other qualified clinician for medical or dental decisions. — Watch next: https://www.youtube.com/watch?v=N3p6okVW9JU
Oral HealthPeriodontal DiseaseHeart Disease
42:38
85K views
Feb 12, 2026
The Heart Attack You Won't See Coming (Even With 'Good' Stats).
50% of people who die of a heart attack have zero prior symptoms. They have no chest pain, no shortness of breath, and often, "normal" cholesterol on a standard panel. In Part 1 of 𝘛𝘩𝘦 𝘔𝘰𝘥𝘦𝘳𝘯 𝘓𝘪𝘱𝘪𝘥 𝘗𝘭𝘢𝘺𝘣𝘰𝘰𝘬, I break down why the standard of care is failing to detect the world's #1 killer until it’s too late. I share the science on why atherosclerosis is actually a pediatric disease, the "cumulative exposure" math that proves early prevention is 3x more effective, and the specific blood markers you need to look at instead of just LDL-C. 🔔 𝐒𝐮𝐛𝐬𝐜𝐫𝐢𝐛𝐞 𝐟𝐨𝐫 𝐏𝐚𝐫𝐭 𝟐 (𝐓𝐡𝐞 𝐓𝐞𝐬𝐭𝐢𝐧𝐠 𝐏𝐫𝐨𝐭𝐨𝐜𝐨𝐥): https://www.youtube.com/@hillarylinmd 📩 𝐆𝐞𝐭 𝐖𝐞𝐞𝐤𝐥𝐲 𝐋𝐨𝐧𝐠𝐞𝐯𝐢𝐭𝐲 𝐔𝐩𝐝𝐚𝐭𝐞𝐬: https://hillarylinmd.com/go/yt 𝐎𝐍 𝐓𝐇𝐈𝐒 𝐄𝐏𝐈𝐒𝐎𝐃𝐄: We dismantle the "plumbing" model of heart disease and replace it with the latest science on lipidology and longevity. • 𝐓𝐡𝐞 "𝐒𝐢𝐥𝐞𝐧𝐭" 𝐊𝐢𝐥𝐥𝐞𝐫: Why your body is evolutionarily designed to *hide* heart disease from you. • 𝐓𝐡𝐞 𝐏𝐞𝐝𝐢𝐚𝐭𝐫𝐢𝐜 𝐄𝐯𝐢𝐝𝐞𝐧𝐜𝐞: Autopsy data showing plaque in 20-year-olds (Korean War & PDAY studies). • 𝐓𝐡𝐞 𝐌𝐞𝐜𝐡𝐚𝐧𝐢𝐬𝐦: How ApoB particles get trapped in the artery wall (The "Response to Retention" model). • 𝐓𝐡𝐞 𝐌𝐚𝐭𝐡 𝐨𝐟 𝐑𝐢𝐬𝐤: Why "Cholesterol-Years" matter more than your current numbers. • 𝐋𝐢𝐟𝐞𝐬𝐭𝐲𝐥𝐞 𝐅𝐚𝐜𝐭𝐨𝐫𝐬: How sleep debt and stress physically damage your endothelium. ⏱ CHAPTERS 0:00 The Silent Statistic: Why Your Doctor Is Flying Blind 1:30 My Family's Cardiac Crisis: Why I Had to Find Out for Myself 3:18 The Pediatric Bombshell: This Disease Starts Before Your 20s 7:39 The False Negative: Why "Normal" Labs Give You a Dangerous Pass 9:29 The Mechanism: How Plaque Actually Forms in Your Arteries 11:20 Foam Cells & Time Bombs: Why Soft Plaque Is the Real Killer 13:39 The Three Drivers: ApoB, Inflammation & Endothelial Damage 16:20 Cholesterol-Years: Why Lifetime Exposure Matters More Than Today's Number 17:00 ApoB vs. LDL: Why You're Measuring the Wrong Thing 18:20 Nature's RCT: What People Born With Low LDL Teach Us 20:41 The Compound Interest Effect: Why Early Treatment Is 3× More Powerful 23:09 The Evolutionary Paradox: Why Our Bodies Were Built to Betray Us 25:00 LDL's Hidden Purpose: Why the Molecule Isn't All Bad 28:00 The Invisible Damage: What Stress & Sleep Debt Do to Your Arteries 31:59 The Growth Rate: How Fast Is Your Plaque Actually Advancing? 33:20 The Information War: Why Cholesterol Denialism Is So Seductive 41:00 What This Means for You: The Stakes, The Opportunity & What's Next About the Show: The Longevity Show with Dr. Hillary Lin takes complex medical research and distills it into practical, easy-to-understand advice for living a longer, healthier life. Covering everything from preventative medicine and metabolic health to the latest breakthroughs in nutrition, exercise, and mental wellness, Dr. Lin gives you the tools you need to thrive. 𝐒𝐂𝐈𝐄𝐍𝐓𝐈𝐅𝐈𝐂 𝐒𝐎𝐔𝐑𝐂𝐄𝐒: •𝘌𝘯𝘰𝘴 𝘦𝘵 𝘢𝘭. (1953): Coronary disease among US soldiers • 𝘍𝘦𝘳𝘦𝘯𝘤𝘦 𝘦𝘵 𝘢𝘭. (2017): Low-density lipoproteins cause ASCVD • 𝘍𝘦𝘳𝘯á𝘯𝘥𝘦𝘻-𝘍𝘳𝘪𝘦𝘳𝘢 𝘦𝘵 𝘢𝘭. (𝘗𝘌𝘚𝘈 𝘚𝘵𝘶𝘥𝘺): Subclinical Atherosclerosis in the Absence of Risk Factors • 𝘉𝘰𝘳é𝘯 𝘦𝘵 𝘢𝘭. (1998): Binding of LDL to proteoglycans (Site B) • 𝘛𝘢𝘸𝘢𝘬𝘰𝘭 𝘦𝘵 𝘢𝘭. (2017): Amygdalar activity and cardiovascular events ABOUT DR. HILLARY LIN: Dr. Hillary Lin is a Stanford-trained physician and the Co-Founder/CEO of CareCore. She explores the cutting edge of longevity medicine, metabolic health, and mental resilience, translating complex science into actionable protocols for a longer, healthier life. GET PERSONALIZED INSIGHTS: Newsletter: https://hillarylinmd.com/go/yt LinkedIn: https://www.linkedin.com/in/hillarylinmd/ Instagram: https://instagram.com/hillarylinmd Twitter/X: https://twitter.com/hillarylinmd CareCore: https://carecore.io DISCLAIMER: Content is for educational purposes only and does not constitute medical advice. Consult your physician for medical decisions. — Watch next: https://www.youtube.com/watch?v=ihJmKmRC65w
Heart DiseaseApoBCholesterol
14:22
3K views
Jan 17, 2026
Stop Cooking With These: A Longevity Physician’s Guide to Seed Oils & Saturated Fat
We’ve been told the same story for 50 years: "Saturated fat is bad, vegetable oil is heart-healthy." But if that’s true, why are we in a global energy crisis of chronic fatigue and metabolic stalling? As a longevity physician, I look at the body like an engineer looks at a high-performance machine. When the engine stalls, I don't blame the driver—I look at the fuel. In this masterclass, we dismantle the "Fat Wars" with clinical nuance. I explain why the Seed Oil debate is often missing the most dangerous variable: Oxidation. We explore the "Two-Hit Theory" of heart disease, how unstable fats create "zombie" membranes in your mitochondria, and why your Air Fryer might be an oxidation accelerator. Most importantly, I provide a practical kitchen protocol to help you rebuild your biology from the cell membrane out. In this episode, we cover: • The Two-Hit Theory: Why LDL volume is only half the problem (and why oxidation is the match that lights the fire). • The Membrane Theory: How Linoleic Acid creates "fragile" cells that leak toxic waste (4-HNE) into your brain. • The Migraine Connection: New NIH data on how specific oils chemically activate your pain receptors (TRPV1). • The Smoke Point Lie: Why "high smoke point" oils can still rot your DNA. • The Official Protocol: My Tier 1, 2, and 3 hierarchy for the longevity-focused kitchen. Chapters 00:00 The Energy Crisis Within Us 01:47 The Two-Hit Theory: Why "Healthy" Oils May Be Driving Heart Disease 04:34 Cellular Sabotage: How Unstable Fats Break Mitochondria & Trigger Pain 07:54 Cooking Myths Debunked: Smoke Points, Olive Oil, & Air Fryer Risks 09:50 The Return of Solid Fats: Why Tallow Wins & Crisco Kills 11:37 The Official Protocol: Tier 1, 2, and 3 Oils for Your Kitchen ✨ Get 5 Easy Longevity Tips & Dr. Hillary Lin's Weekly Newsletter for Free: https://hillarylinmd.com/go/yt About the Show: The Longevity Show with Dr. Hillary Lin takes complex medical research and distills it into practical, easy-to-understand advice for living a longer, healthier life. Covering everything from preventative medicine and metabolic health to the latest breakthroughs in nutrition, exercise, and mental wellness, Dr. Lin gives you the tools you need to thrive. About Dr. Hillary Lin and CareCore Dr. Hillary Lin is a Stanford MD and CEO/Co-founder of CareCore, a platform helping clinicians launch personalized longevity practices powered by evidence-based protocols and AI-driven tools. Follow for insights on transforming care delivery through precision medicine. Connect with Dr. Hillary Lin: LinkedIn: https://www.linkedin.com/in/hillarylinmd/ Instagram: https://www.instagram.com/hillarylinmd Facebook: https://www.facebook.com/hillarylinmd X: https://twitter.com/hillarylinmd TikTok: https://www.tiktok.com/@hillarylinmd Disclaimer: This podcast is for informational purposes only and does not constitute medical advice, diagnosis, or treatment. No doctor-patient relationship is formed. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition. Use of this information is at your own risk. — Watch next: https://www.youtube.com/watch?v=N3p6okVW9JU
Seed OilsSaturated FatNutrition
16:06
4K views
Dec 30, 2025
Normal Labs But Still Exhausted? The Mitochondrial Problem Doctors Miss
If you’re sleeping well, eating clean, exercising—and still exhausted—this may be an engine problem, not a fuel problem. This is Part 1 of my Mitochondrial Health Series, where I start with the foundation: mitophagy—your body’s ability to clear damaged mitochondria. In longevity medicine, I call this mitophagy failure: damaged mitochondria (“zombie batteries”) stop producing clean energy and leak signals that can trigger inflammation, brain fog, and that 2 p.m. crash. In this video, I break down: • Why zombie mitochondria can keep you stuck in “sickness behavior” • The key biology: PINK1 + Parkin (how your cells tag and remove broken mitochondria) • My 4-step energy protocol: 14–16 hr overnight fasting, Zone 2 cardio, heat (sauna/hot bath), and urolithin A + spermidine • The NAD+ trap: why NMN/NR can backfire if you “fuel” before you “clean” *Chapters:* 00:00 The "Zombie Battery" Cause of Fatigue 01:54 Why Your Cells Think They Are Dying 04:43 The Cleanup Crew: PINK1 & Parkin 07:02 Protocol 1: The "Janitor" Fast (AMPK vs. mTOR) 08:44 Protocol 2: Why HIIT Might Be Making You Tired 09:59 Protocol 3: Heat Shock Proteins & Sauna 11:30 Protocol 4: Supplements (Urolithin A, Spermidine) & The NAD+ Mistake 15:18 Summary: The 4-Step Energy Protocol ✨ Get 5 Easy Longevity Tips & Dr. Hillary Lin's Weekly Newsletter for Free: https://www.hillarylinmd.com/subscribe *About the Show:* The Longevity Show with Dr. Hillary Lin takes complex medical research and distills it into practical, easy-to-understand advice for living a longer, healthier life. Covering everything from preventative medicine and metabolic health to the latest breakthroughs in nutrition, exercise, and mental wellness, Dr. Lin gives you the tools you need to thrive. *About Dr. Hillary Lin and Care Core* Dr. Hillary Lin is a Stanford MD and CEO/Co-founder of Care Core, a platform helping clinicians launch personalized longevity practices powered by evidence-based protocols and AI-driven tools. Follow for insights on transforming care delivery through precision medicine. *Connect with Dr. Hillary Lin:* Instagram: https://www.instagram.com/hillarylinmd Facebook: https://www.facebook.com/hillarylinmd X: https://twitter.com/hillarylinmd TikTok: https://www.tiktok.com/@hillarylinmd *Disclaimer:* This podcast is for informational purposes only and does not constitute medical advice, diagnosis, or treatment. No doctor-patient relationship is formed. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition. Use of this information is at your own risk.
MitochondriaFatigueCellular Health
59:59
62K views
Dec 20, 2025
The "Normal" Cholesterol Myth: Detecting the Widowmaker Before It Strikes
Heart disease is still the #1 killer worldwide, yet 50-75% of people who suffer a heart attack have "normal" cholesterol levels. Traditional cardiology waits for symptoms—chest pain, shortness of breath, or cardiac arrest—before treating the problem. Dr. John Osborne, MD, PhD, argues this is like waiting for Stage 4 cancer before ordering a screening. In this episode, we dismantle "20th Century Cardiology." We explain why standard EKGs and stress tests fail to detect early plaque and why the "Cardiac Colonoscopy"—AI-enabled CCTA—is the only way to truly visualize your risk. We also dive deep into advanced reversal protocols, including the use of Colchicine for inflammation, the "Keto Paradox," and the genetic biomarkers (Lp(a) and ApoB) that you need to request immediately. Topics Covered: • The Failure of "Gold Standards": Why stress tests miss 30-40% of dangerous blockages. • Soft Plaque vs. Hard Plaque: Understanding the difference between stable calcium and the "lava" that causes sudden death. • Advanced Imaging: How AI CCTA visualizes the vessel wall (the "donut") rather than just the hole. • Protocols for Reversal: The role of Colchicine, PCSK9 inhibitors, and statins in shrinking plaque. • The Keto Paradox: Can you have healthy arteries with high cholesterol? • Genetics: Why everyone needs to test for Lipoprotein(a) once in their life. ⏱ CHAPTERS 0:00 Introduction: Dr. John Osborne, Preventive Cardiologist & Lipidologist 1:32 What If We Treated Heart Disease Like Cancer? The Case for Prevention 4:45 Why Your Standard Cardiology Workup Misses the Mark 6:45 The Problem With Stress Tests, EKGs & Echos 10:08 The Donut vs. The Hole: How Your Artery Hides Deadly Plaque 12:05 Soft Plaque vs. Calcified Plaque: Which One Actually Kills You 16:03 The Cardiac Colonoscopy: Why AI Imaging Changes Everything 19:54 Calcium Score vs. CT Angiography: What You Actually Need 24:52 How AI Detects the Soft Plaque That Human Eyes Miss 28:34 What It Costs & Who Should Get Scanned 31:04 Lp(a): The Cholesterol Marker Almost Nobody Tests For 34:10 Which Blood Tests Actually Predict Risk (And Which Are Useless) 37:29 The Cholesterol Paradox: Inflammation, Sticky Vessels & The Keto Debate 44:13 Reversing Plaque: Colchicine, Statins, PCSK9i & Personalized Protocols 53:00 Gene Editing & Emerging Therapies: The Frontier of Cardiac Medicine 57:13 The Mission: Eliminating Heart Disease in Our Lifetime About Dr. John Osborne: Dr. John Osborne is a Preventative Cardiologist and Lipidologist based in Dallas. He holds an MD and PhD in cardiovascular physiology and founded State of the Heart Cardiology. He is the Co-Founder and Chief Medical Officer of ClearCardio, pioneering the use of AI in cardiac imaging to detect and reverse heart disease before it becomes fatal. YouTube: https://www.youtube.com/@ClearCardio Website: https://clearcardio.com/ Instagram: https://www.instagram.com/clearcardio/ TikTok: https://www.tiktok.com/@clearcardio ✨ Get 5 Easy Longevity Tips & Dr. Hillary Lin's Weekly Newsletter for Free: https://hillarylinmd.com/go/yt About the Show: The Longevity Show with Dr. Hillary Lin takes complex medical research and distills it into practical, easy-to-understand advice for living a longer, healthier life. Covering everything from preventative medicine and metabolic health to the latest breakthroughs in nutrition, exercise, and mental wellness, Dr. Lin gives you the tools you need to thrive. About Dr. Hillary Lin and CareCore Dr. Hillary Lin is a Stanford MD and CEO/Co-founder of CareCore, a platform helping clinicians launch personalized longevity practices powered by evidence-based protocols and AI-driven tools. Follow for insights on transforming care delivery through precision medicine. Connect with Dr. Hillary Lin: LinkedIn: https://www.linkedin.com/in/hillarylinmd/ Instagram: https://www.instagram.com/hillarylinmd Facebook: https://www.facebook.com/hillarylinmd X: https://twitter.com/hillarylinmd TikTok: https://www.tiktok.com/@hillarylinmd Disclaimer: This podcast is for informational purposes only and does not constitute medical advice, diagnosis, or treatment. No doctor-patient relationship is formed. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition. Use of this information is at your own risk. — Watch next: https://www.youtube.com/watch?v=fX33g1zFZSo
CholesterolCAC ScoreWidowmaker
25:26
1K views
Dec 8, 2025
Healthspan vs Lifespan: How to Age Better, Not Just Longer
Most people do not actually want more birthdays if those years mean frailty, isolation, and losing independence. The better target is healthspan: more years with mobility, cognitive clarity, purpose, connection, and the ability to do what you value. In this solo episode, Dr. Hillary Lin breaks down the healthspan–lifespan gap: why acute-care systems are often better built to rescue illness than to protect long-term function, how work, cities, healthcare incentives, social norms, stress, sleep, food, and reward loops shape healthy aging, and what small practical habits can protect function over time. Important: this episode critiques structural incentives and daily habits, but it is not a recommendation to avoid medical care, skip evidence-based screening, or replace treatment with lifestyle alone. Prevention, lifestyle, and medical care should work together. Use this as a framework for thinking about healthy aging, not individualized medical advice. Topics covered: • Why “living to 100” is the wrong question • The difference between lifespan and healthspan • How reactive healthcare, insurance, and access barriers can work against prevention • Why hustle culture, time scarcity, food access, and built environments shape health • How short-term reward loops, stress, sleep, hormones, and aging biology make healthy choices harder • Practical healthspan habits: hydration, movement, morning light, nutrient-dense meals, sleep consistency, stress relief, preventive appointments, social movement, weekly reflection, and redefining success Chapters: 00:00 - Why living to 100 is the wrong question 01:28 - The healthspan-lifespan gap 05:06 - Why healthcare often favors sick care over prevention 10:49 - Hustle culture, cities, time scarcity, and social barriers 14:00 - Why biology makes healthy choices harder 22:19 - 10 practical healthspan habits 25:16 - Healthspan as a shared project Get Dr. Hillary Lin’s weekly newsletter: https://hillarylinmd.com/go/yt Learn more: https://www.hillarylinmd.com About the show: The Longevity Show with Dr. Hillary Lin translates medical research and clinical reasoning into practical, careful conversations about healthspan, prevention, and longevity. Connect with Dr. Hillary Lin: LinkedIn: https://www.linkedin.com/in/hillarylinmd/ Instagram: https://www.instagram.com/hillarylinmd Facebook: https://www.facebook.com/hillarylinmd X: https://x.com/hillarylinmd TikTok: https://www.tiktok.com/@hillarylinmd Disclaimer: This podcast is for general informational and educational purposes only and does not constitute medical advice, diagnosis, treatment, or the practice of medicine. No doctor-patient relationship is formed. Do not start, stop, or change exercise, nutrition, supplements, medications, screening, or treatment plans based on this episode. Talk with a qualified clinician about your own symptoms, medical conditions, medications, risk factors, and care plan. — Watch next: https://www.youtube.com/watch?v=N3p6okVW9JU
HealthspanLifespanLongevity Philosophy
31:50
8K views
Nov 21, 2025
The Cholesterol You Can’t Diet Away: Lp(a) Explained
20% of the population has high Lipoprotein(a), yet most doctors don't test for it until it’s too late. Lp(a) is an independent genetic risk factor that triples your risk of heart attack and stroke. If you've never had this specific blood test, this video is a must-watch. I explain exactly what it is and how to ask for the test. In this episode, we cover what Lp(a) is, why it is strongly inherited, and which groups are most affected. You will learn how to test for it, what levels mean, and why new RNA based treatments could change cardiovascular care in the next few years. If you have a family history of heart disease or “normal” cholesterol with lingering symptoms, this is essential viewing. What you will learn: • Why Lp(a) is missed on standard cholesterol tests • How genetics set your Lp(a) level for life • Ethnic differences in Lp(a) and who should test today • Why Lp(a) promotes plaque, inflammation, and clots • Current options. PCSK9 inhibitors, apheresis, and lifestyle strategy • New RNA based therapies that may drop Lp(a) by up to 90 percent If heart disease runs in your family, ask your clinician for an Lp(a) test. This one number can change your prevention plan. #lipoproteina #lpa #cholesterol #heartdisease #strokeprevention #cardiovascularhealth #heartattack #cardiologist #cholesteroltest #preventivemedicine #genetics #atherosclerosis #pcsk9 #rnatherapy #hillarylinmd ✨ Get 5 Easy Longevity Tips & Dr. Hillary Lin's Weekly Newsletter for Free: https://hillarylinmd.com/go/yt Chapters: 0:00 The overlooked cholesterol particle 1:30 Who is more likely to have high Lp(a) 3:00 What Lp(a) actually is 4:30 How Lp(a) damages arteries 7:30 Inflammation and unstable plaque 9:00 Clotting risk and lifelong exposure 12:00 When to test and what levels mean 13:30 How the rest of your lipid panel fits in 16:30 Lifestyle: what helps and what does not 22:30 PCSK9 inhibitors and Lp(a) 24:00 RNA-based therapies in development 27:00 Emerging treatments and takeaways About the Show: The Longevity Show with Dr. Hillary Lin takes complex medical research and distills it into practical, easy-to-understand advice for living a longer, healthier life. Covering everything from preventative medicine and metabolic health to the latest breakthroughs in nutrition, exercise, and mental wellness, Dr. Lin gives you the tools you need to thrive. About Dr. Hillary Lin and CareCore Dr. Hillary Lin is a Stanford MD and CEO/Co-founder of CareCore, a platform helping clinicians launch personalized longevity practices powered by evidence-based protocols and AI-driven tools. Follow for insights on transforming care delivery through precision medicine. Connect with Dr. Hillary Lin: LinkedIn: https://www.linkedin.com/in/hillarylinmd/ Instagram: https://www.instagram.com/hillarylinmd Facebook: https://www.facebook.com/hillarylinmd X: https://twitter.com/hillarylinmd TikTok: https://www.tiktok.com/@hillarylinmd Disclaimer: This podcast is for informational purposes only and does not constitute medical advice, diagnosis, or treatment. No doctor-patient relationship is formed. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition. Use of this information is at your own risk. — Watch next: https://www.youtube.com/watch?v=fX33g1zFZSo
Lp(a)GeneticsCholesterol
44:26
1K views
Nov 14, 2025
Full-Body MRI Screening: What It Can Find, What It Can Miss
Whole-body MRI can sometimes find important findings earlier, but it is not a substitute for evidence-based cancer screening and it is not a universal recommendation for every healthy person. In this episode, Dr. Hillary Lin speaks with Dr. A. Alexander, a board-certified radiologist, former team physician for the Lakers and Dodgers, and CEO of CoreViva, about thin-slice MRI, early detection, false positives, incidental findings, cost, and patient selection. The goal is not to say “everyone should get a scan.” The goal is to understand what full-body MRI may detect, what it can miss, why protocols and radiologist review matter, and how to think about follow-up with your own clinician. We also discuss why standard screening still matters: mammography/breast imaging when appropriate, colonoscopy or stool-based colorectal screening, cervical cancer screening, lung CT for eligible high-risk patients, skin exams, and risk-based testing. This conversation includes discussion of CoreViva because of Dr. Alexander’s role. It is educational only and not individualized medical advice. If you are considering whole-body MRI, especially because of symptoms, family history, genetic risk, prior cancer, aneurysm risk, or health anxiety, discuss the tradeoffs with a qualified clinician and/or radiologist. Topics Covered: • What full-body MRI can and cannot detect. • Why “early detection” depends on the disease, protocol, image quality, radiologist expertise, and what happens after the scan. • False positives, incidental findings, false reassurance, and downstream follow-up. • Why whole-body MRI does not replace standard cancer screening. • Where body composition, visceral fat, fatty liver, musculoskeletal findings, and aneurysm screening may fit into a broader clinical picture. • How to think about scan cost, reports, physician review, and whether results would actually change care. • The difference between a proactive health tool and a universal screening recommendation. Chapters: 00:00 What full-body MRI promises and where the nuance starts 00:57 What caloric restriction taught us about aging 07:57 How elite athletes master longevity habits 10:25 Why CoreViva built a thin-slice MRI model 12:59 Inside a CoreViva scan: what patients experience 16:32 What full-body MRI may reveal and what it can miss 25:23 The future of prevention and longevity medicine 39:17 The 3 habits that outlive us all ✨ Get 5 Easy Longevity Tips & Dr. Hillary Lin's weekly newsletter: https://hillarylinmd.com/go/yt About the Show: The Longevity Show with Dr. Hillary Lin takes complex medical research and turns it into practical, evidence-aware guidance for living longer and better. Topics include preventive medicine, metabolic health, cardiovascular risk, hormones, exercise, nutrition, mental resilience, and the science behind longevity claims. About Dr. Hillary Lin: Dr. Hillary Lin is a Stanford-trained physician and the Co-Founder/CEO of CareCore. She explores longevity medicine, metabolic health, and clinical decision-making, translating complex science into practical frameworks for patients, clinicians, and health-curious adults. Connect with Dr. Hillary Lin: Website: https://www.hillarylinmd.com Newsletter: https://hillarylinmd.com/go/yt LinkedIn: https://www.linkedin.com/in/hillarylinmd/ Instagram: https://www.instagram.com/hillarylinmd X: https://twitter.com/hillarylinmd TikTok: https://www.tiktok.com/@hillarylinmd CareCore: https://carecore.io Disclaimer: This content is for educational purposes only and does not constitute medical advice, diagnosis, screening recommendation, or treatment. No doctor-patient relationship is formed. Always seek the advice of your physician or other qualified healthcare provider with questions about symptoms, cancer risk, aneurysm risk, imaging, screening, testing, or treatment decisions. #FullBodyMRI #WholeBodyMRI #PreventiveMedicine #MRIScreening #LongevityMedicine — Watch next: https://www.youtube.com/watch?v=N3p6okVW9JU
Full-Body MRICancer ScreeningPreventive Medicine
24:29
7K views
Oct 28, 2025
Toxic Metals in Your Body? How to Test & Detox (Pt. 2)
Could you be carrying years of toxic metal exposure in your body without knowing it? This is Part 2 of our deep dive into heavy metal toxicity—a silent health threat linked to fatigue, brain fog, aging, and chronic disease. In this episode, we reveal exactly how to test your body, interpret your results, and detox effectively using both natural remedies and advanced therapies. 🧬 What You’ll Learn in Part 2: ✅ The difference between blood, hair, and urine metal testing ✅ Food & supplement protocols for detox (zinc, magnesium, glutathione & more) ✅ Which “detox trends” are hype vs. scientifically proven ✅ Advanced options: chelation, nano-chelators, red light therapy & more ✅ How to protect your family, home & longevity from heavy metal exposure 📌 Symptoms we cover: fatigue, anxiety, insomnia, brain fog, premature aging, immune issues 📈 Heavy metals are everywhere—from water to cosmetics—and they're linked to serious health risks. But now you’ll know exactly what to do about it. Chapters: 00:00 Introduction to Heavy Metals and Health Risks 00:49 What Are Heavy Metals and Why Should You Care? 01:58 How to Test for Heavy Metals in Your Body 08:38 Detox Strategies: Dietary Approaches 15:12 Detox Strategies: Lifestyle Adjustments 17:30 Heavy Metal Detox: Advanced Therapies and Emerging Tech #HeavyMetalDetox #ToxicExposure #ChelationTherapy #MercuryPoisoning #LeadToxicity #BrainFogFix #FunctionalMedicine #FatigueRelief #WellnessTips #LongevityHack #NaturalHealing #HealthPodcast #DetoxNaturally #HowToDetox #Part2 #HillaryLinMD #HillaryLin #Longevity ✨ Get 5 Easy Longevity Tips & Dr. Hillary Lin's Weekly Newsletter for Free: https://hillarylinmd.com/go/yt About the Show: The Longevity Show with Dr. Hillary Lin takes complex medical research and distills it into practical, easy-to-understand advice for living a longer, healthier life. Covering everything from preventative medicine and metabolic health to the latest breakthroughs in nutrition, exercise, and mental wellness, Dr. Lin gives you the tools you need to thrive. About Dr. Hillary Lin and CareCore Dr. Hillary Lin is a Stanford MD and CEO/Co-founder of CareCore, a platform helping clinicians launch personalized longevity practices powered by evidence-based protocols and AI-driven tools. Follow for insights on transforming care delivery through precision medicine. Connect with Dr. Hillary Lin: LinkedIn: https://www.linkedin.com/in/hillarylinmd/ Instagram: https://www.instagram.com/hillarylinmd Facebook: https://www.facebook.com/hillarylinmd X: https://twitter.com/hillarylinmd TikTok: https://www.tiktok.com/@hillarylinmd Disclaimer: This podcast is for informational purposes only and does not constitute medical advice, diagnosis, or treatment. No doctor-patient relationship is formed. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition. Use of this information is at your own risk. — Watch next: https://www.youtube.com/watch?v=N3p6okVW9JU
Heavy MetalsDetoxTesting
40:46
5K views
Oct 15, 2025
Heavy Metals and Health: Sources, Risks & What to Know Before Detox
Heavy metals like lead, mercury, cadmium, and arsenic can matter for health, but “detox” advice online often skips the most important step: understanding exposure, testing, and clinical context. In this episode, Dr. Hillary Lin walks through where toxic metals can show up, which exposure patterns deserve attention, how they may affect the body, and how to reduce avoidable exposure without turning everyday life into toxin panic. Important caveat: symptoms like fatigue, brain fog, headaches, digestive issues, and hormone changes have many possible causes. Heavy-metal testing and treatment should be interpreted with a qualified clinician, and chelation or detox protocols should not be started from a YouTube video. What You'll Learn: - Why lead, mercury, cadmium, and arsenic are treated differently from essential trace minerals - How exposure can happen through food, water, paint or dust, cosmetics, cookware, spices, supplements, and some occupational or environmental settings - What the evidence suggests about cardiovascular, neurologic, kidney, liver, reproductive, and cancer-related risks — without assuming every symptom is caused by metals - Why children, pregnancy, high-exposure jobs or hobbies, and older housing deserve extra caution - Practical ways to reduce exposure: safer renovation habits, food-safe ceramics, water filtration when appropriate, reputable spice and supplement sourcing, and clinician-guided testing Chapters: 00:00 Understanding Heavy Metal Toxicity 02:17 How Heavy Metals Can Affect Cells and Energy 09:11 Health Risks Linked to Heavy-Metal Exposure 21:06 Common Sources of Heavy-Metal Exposure 29:42 Less Obvious Places Metals Can Hide 36:11 Practical Ways to Reduce Exposure ✨ Get 5 Easy Longevity Tips & Dr. Hillary Lin's Weekly Newsletter for Free: https://hillarylinmd.com/go/yt About the Show: The Longevity Show with Dr. Hillary Lin takes complex medical research and turns it into practical, clinically grounded guidance for living a longer, healthier life. Topics include preventive medicine, metabolic health, cardiovascular risk, brain health, nutrition, exercise, testing, and the tradeoffs behind popular longevity trends. About Dr. Hillary Lin and CareCore: Dr. Hillary Lin is a Stanford-trained physician and co-founder/CEO of CareCore, a platform helping clinicians and founders build personalized, evidence-informed longevity practices. Follow for clear, science-rich conversations about healthspan, medicine, and the future of care delivery. Connect with Dr. Hillary Lin: 📩 Free Weekly Newsletter: https://hillarylinmd.com/go/yt 🔔 YouTube: https://www.youtube.com/@hillarylinmd 📸 Instagram: https://www.instagram.com/hillarylinmd 💼 LinkedIn: https://www.linkedin.com/in/hillarylinmd/ 𝕏 Twitter/X: https://twitter.com/hillarylinmd ▶ TikTok: https://www.tiktok.com/@hillarylinmd 📘 Facebook: https://www.facebook.com/hillarylinmd 🏥 CareCore: https://carecore.io Disclaimer: This podcast is for informational purposes only and does not constitute medical advice, diagnosis, or treatment. It does not diagnose heavy-metal toxicity and is not a detox, chelation, supplement, or treatment protocol. If you are concerned about possible heavy-metal exposure, elevated test results, pregnancy or child exposure, kidney or liver disease, neurologic symptoms, or acute poisoning, speak with a qualified clinician or poison-control resource. No doctor-patient relationship is formed. Use of this information is at your own risk. — Watch next: https://www.youtube.com/watch?v=N3p6okVW9JU
Heavy MetalsAgingEnvironmental Toxins