Actionable Health & Longevity

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Latest Content

The Longevity Letter #17: GRAIL's Cancer Test Just Failed Its Big Trial. Here's Why I Still Use It.

Despite sensational headlines about GRAIL's recent clinical trial missing its primary endpoint, the nuanced data, a booming competitive market, and new Medicare legislation prove that the multi-cancer early detection (MCED) field is actually advancing rapidly as a vital piece of comprehensive, personalized cancer screening.

The Longevity Letter #16: He didn't run until 66. At 82, he beats 20-yo athletes.

A groundbreaking new study proves lifestyle changes can actively reverse epigenetic aging, a finding brought to life by the story of an 82-year-old mechanic with the aerobic capacity of a 30-year-old. Inside, we break down the science of "negotiable" biological age and the specific cardio protocol you can use to lower yours.

The Heart Attack You Won't See Coming (Even With 'Good' Stats).

Challenge the outdated "plumbing" model of heart disease and discover why standard cholesterol tests often miss the world’s #1 killer. We break down the science of ApoB and "cholesterol-years," showing why cumulative exposure math is the key to prevention that is three times more effective.

Why I prescribe Rapamycin - but not to most of my patients

Discover why 2026 research has shifted Rapamycin from a "cellular cleanup crew" to a powerful shield for your DNA. Dive into the latest human data on immune rejuvenation and muscle health, and see the exact clinical protocol used to balance longevity gains with metabolic safety.

The Longevity Letter #15: Is 50% of your lifespan already "decided"?

A major new study reveals that over 50% of your lifespan is genetic—but here’s why that actually validates precision medicine and the exact high-intensity exercise protocol proven to reverse biological aging.

The Longevity Letter #14: My Unusual Body Recomp Stack

Discover why just 15 minutes of "fast" walking cuts mortality risk by 20% (even in populations often ignored by research), the simple $20 generic drug that might mimic Ozempic without the nausea, and why Harvard says "hybrid" athletes live longer.